Crestor is a statin like Lipitor. One type of debris created in this muscle breakdown is a protein called myoglobin. The most common side effects for statin patients affect the muscles. The recovery time averages about three weeks. The degree of ALT level elevation can show the seriousness of liver injury. Relationship of Sex to Diabetes Risk in Statin Trials. This website and its content may be deemed attorney advertising. © 2005 - 2019 WebMD LLC. Hemorrhagic Stroke. Side effects of Crestor (rosuvastatin) include: About 1 in 10,000 patients taking statins develop a severe muscle condition. et al. Several studies have found a higher risk of hemorrhagic stroke in populations with low cholesterol levels. Studies have shown taking statins may increase a person’s risk of developing diabetes by 9 to 48 percent. The Women’s Health Initiative also conducted a study. Retrieved, Mendes, P. et al. ALERT: Your health is top priority. They found people taking the medicine were nearly four times more likely to report memory loss within 30 days after starting the drug. Researchers looked at data from the 18,000-patient study. (2005, June 13). Drugwatch partners with Physicians’ Review Network Inc. to enlist specialists. An estimated one in every 10,000 statin users will develop rhabdomyolysis. Statin Use and Risk of Diabetes Mellitus. Things to remember when you fill your prescription. Retrieved, Harvard Medical School. (2018, November). For more information, visit our sponsors page. However, as required by the new California Consumer Privacy Act (CCPA), you may record your preference to view or remove your personal information by completing the form below. We’re committed to providing reliable COVID-19 resources to keep you informed and safe. Your chances of getting muscle problems are higher if you: Statin Side effects: How common are they? In addition, there have been reports of memory loss possibly linked to Crestor use. Warning signs of rhabdomyolysis include muscle aches and dark-colored urine. Retrieved, NIH Medline Plus. Myalgia is the most common of the muscle-related side effects. Patients with kidney impairment are also at an increased risk for myalgia. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Statins and Liver Injury. Retrieved, Heo, J.H. Crestor Label. Do Not Sell My Info. (2012, August). Retrieved, McKinney, J.S. (2015, March 15). CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Memory impairment may be reversible by temporarily discontinuing Crestor. Patients should not stop taking a prescription drug without consulting a doctor. Statin Therapy and the Risk of Intracerebral Hemorrhage; A Meta-Analysis of 31 Randomized Controlled Trials. Muscle Pain If experienced, these tend to have a Less Severe expression 1. Retrieved, Thapar, M. et al. Researchers found the diabetes risk increased to 48 percent among women taking statins. The drug may also be linked to decreased cognition, such as memory loss and amnesia. Retrieved, Chogtu, B. The risk increases in patients 65 years and older. But in the drug’s first year, the number of rhabdomyolysis cases among Crestor users was higher than for other statins. Injured by a prescription drug or defective medical device? Effect and Safety of Rosuvastatin in Acute Ischemic Stroke. et al. © 2020 Drugwatch.com Privacy Policy/ The information on this website is proprietary and protected. Rhabdomyolysis is a type of skeletal muscle damage that can lead to kidney damage and sometimes death. These effects have been seen in at least 2 percent of people taking the drug in clinical trials. But statins may increase the risk of hemorrhagic strokes. Please read our disclaimer for more information about our website. (2013, July). The most severe muscle disorder related to statins is rhabdomyolysis. Reports included cases of memory loss, forgetfulness, amnesia, memory impairment and confusion. Reviewer specialties include internal medicine, gastroenterology, oncology, orthopedic surgery and psychiatry. Are taking certain other medicines while … Patients who catch liver injury quickly can recover within one to two months after stopping the drug. It tells health care professionals to advise patients to “report unexplained muscle pain, tenderness, or weakness.” The warning mentions myopathy and rhabdomyolysis specifically. Statin-Induced Rhabdomyolysis: A Comprehensive Review of Case Reports. (2004, June 26). Calling this number connects you with a Drugwatch representative. Letter Demonstrating that Rosuvastatin (Crestor) Has Higher Rates of Rhabdomyolysis Compared to Other Statins. This site complies with the HONcode standard for trustworthy health information: Verify here. Retrieved, Public Citizen. Studies also show as many as three in every 100 patients taking Crestor experience side effects from elevated liver enzymes. Rosuvastatin Calcium (Marketed as Crestor) Information. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Retrieved, Liao, J.K. (2006, December 15). What to Believe and Do About Statin-Associated Adverse Effects. (n.d.). Myopathy is a group of disorders in which muscle fibers do not function properly. If experienced, these tend to have a Severe expression 1. Retrieved, Peck, P. (2005, May 23). The condition is considered rare. Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality. AstraZeneca recommends doctors order blood tests to check patients’ livers before prescribing the drug. (2012, February 1). and Kostis, W.J. We will direct you to one of our trusted legal partners for a free case review. If experienced, these tend to have a Severe expression, If experienced, these tend to have a Less Severe expression. Crestor’s side effects range from common, relatively mild reactions such as headaches to a rare, severe condition called rhabdomyolysis, which has been linked to kidney damage and death. (2016, November 15). Head Pain 3. Drugwatch.com is sponsored by law firms. Liver injury is rare but if it happens, it usually occurs two to four months into Crestor therapy. (2016, January). Crestor prevents recurrence of ischemic stroke. PRN is a nationally recognized leader in providing independent medical reviews. Retrieved, Luvai, A. et al. Rosuvastatin: A Review of the Pharmacology and Clinical Effectiveness in Cardiovascular Disease. It is not a substitute for professional medical advice, diagnosis or treatment. The company also tells patients to immediately call their doctors if they experience certain symptoms. Researchers continued to find previously unknown or underestimated risks of serious side effects. Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein. Crestor’s side effects range from common, relatively mild reactions such as headaches to a rare, severe condition called rhabdomyolysis, which has been linked to kidney damage and death. Retrieved, Goodarzi, M.O. Common side effects can include: headache muscle pain stomach pain feeling weak nausea If you found our resources and information helpful, please take a minute to review us on Facebook and Google. The agency based its decision on studies and adverse event reports. Retrieved, Kaufman, M. (2005, March 3). The conditions are reversible by discontinuing the drug temporarily. Rhabdomyolysis causes skeletal muscle tissue to break down rapidly and travel into the bloodstream. 1 South Orange Ave, Suite 201, Orlando, FL 32801. One of our content team members will be in touch with you soon. WebMD does not provide medical advice, diagnosis or treatment. Retrieved, Bottorff, M.B. (2006, August 10). Retrieved, FDA. Other possible serious side effects of statins include hemorrhagic stroke, Type 2 diabetes and liver damage. As are patients taking cyclosporine, atazanavir/ritonavir, lopinavir/ritonavir or simeprevir. The agency believed other statins already on the market had a similar rate of rhabdomyolysis. Dangers of Rosuvastatin Identified before and after FDA Approval. Crestor’s label carries a warning about skeletal muscle effects. As blood carrying myoglobin passes through the organs, it can cause serious problems including kidney failure. (2008, November 20). (2015, July 10). Crestor May Pose Risk of Muscle Damage. Please seek the advice of a medical professional before making health care decisions. Side effects not requiring immediate medical attention Body aches or pain congestion dry or sore throat runny nose tender, swollen glands in the neck voice changes How Long Does Coronavirus Live On Surfaces? Crestor’s label says the conditions can happen at any time after taking Crestor. Any unauthorized or illegal use, copying or dissemination will be prosecuted. (n.d.). (n.d.) Rhabdomyolysis. Crestor may also increase the chances of liver damage and diabetes.
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