After a flood, are food and medicines safe to use? Niacin to boost your HDL, 'good,' cholesterol, Nuts and your heart: Eating nuts for heart health. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. With this tendency in mind, it's important to remember that medications are only part of the package when it comes to lowering cholesterol, according to the Cleveland Clinic. Statins: Actions, side effects and administration. Indeed, as the Food and Drugs Administration points out, the drug itself is not associated with any significant changes in weight, based on clinical trial data cited on the pravastatin label. Statins block a substance your liver needs to make cholesterol. But this side effect tends to occur more often in people who are already at a higher risk of diabetes. All rights reserved. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Try coenzyme Q10 supplements. There's a long list of other medications that your doctor may prescribe, including other statins, such as the popular drug Lipitor. However, studies have found that nearly 30 percent of people stopped taking the pills because of muscle aches even when they were taking a placebo. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes. Alonso R, et al. any of the products or services that are advertised on the web site. This content does not have an Arabic version. Because of this, be sure your doctor is aware of all drugs you take, including any that have been prescribed by other physicians, if pravastatin is being considered. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins. Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Statin intolerance. diagnosis or treatment. Drugs called bile acid binding resins, including cholestyramine (Prevalite) and colesevelam (Welchol), can work to decrease LDL levels, too, according to the Mayo Clinic, as can the cholesterol absorption inhibitor drug ezetimibe (Zetia) and various combinations of these drugs. Remember that statin medications can reduce your risk of a heart attack or stroke, and the risk of life-threatening side effects from statins is very low. European Heart Journal. If the increase is only mild, you can continue to take the drug. Statin-induced muscle syndromes. Here are six tips to help you get started. While statins are highly effective and safe for most people, they have been linked to muscle pain, digestive problems and mental fuzziness in some people who take them and may rarely cause liver damage. The potential muscular side effects occur in about 10 to 20 percent of people who take statins, but he says that "pravastatin is probably the statin with the least frequency of muscle-related side effects.". If you have read about the potential side effects of statins, you may be more likely to blame your symptoms on the medication, whether or not they're truly caused by the drug. Paired with diet and lifestyle changes, medication can help lower dangerously high levels of low-density lipoprotein (LDL) cholesterol, known as the bad type. Use of this web site constitutes acceptance of the LIVESTRONG.COM FREE book offer – Mayo Clinic Health Letter, Statin side effects Weigh the benefits and risks, Advertising and sponsorship opportunities, Taking multiple medications to lower your cholesterol, Having certain conditions such as hypothyroidism or neuromuscular disorders including amyotrophic lateral sclerosis (ALS), Amiodarone (Cordarone, Pacerone), a medication for irregular heart rhythms, Gemfibrozil (Lopid), another variety of cholesterol drug, HIV treatments called protease inhibitors such as saquinavir (Invirase) and ritonavir (Norvir), Some antibiotic and antifungal medications, such as clarithromycin and itraconazole (Onmel, Sporanox), Some immunosuppressant medications, such as cyclosporine (Gengraf, Neoral, Sandimmune).
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