Development Office We asked BWH scientists to share examples of translational research that has made a difference to them—and the world. We could start, for example, by dedicating sections of our journals to translational research. Brigham and Women’s Hospital “One of the powers of translational research is the inspiration we draw from patients. Associate Radiologist and Medical Director of Cross-Sectional Interventional Radiology, Bringing Evidence to Prescribing Conversations, Semiautomatic Rifles Contribute to More Gun Deaths, Injuries. Thanks for letting us know that this page . Opening doors to new frontiers in research and care. CF req… Psychology students are taught about the differences between basic and applied research. Think about it. Translational research – a term often used interchangeably with translational medicine or translational science or bench to bedside – is an effort to build on basic scientific research to create new therapies, medical procedures, or diagnostics.Basic biomedical research is based on studies of disease processes using, for example, cell cultures or animal models. I wrote that Monitor piece because of growing concern in the basic research community of psychology about the emerging priority of translational research at NIH. It may or may not be recognized as translational research, but that’s what it is. So we ask patients if we can collect their blood samples before and after treatment to understand how their immune system changes with treatment. Co-Director, Human Immunology Center, “D.A. Beyond health-related matters, psychology enjoys fantastic translation in areas such as human factors, education, organizational behavior, decision-making, environmental design, and social influence. It is time to make translation a center piece of psychology, to celebrate it, and to communicate it. Perhaps one day we’ll see entire journals of translational psychology. Translational Research in Psychology: An Instructive Case Arthur P. Sullivan, PhD Touro College and University System 43 W 23rd St., New York NY 10010, USA Penny Sullivan-Nunes, M.S. Translational research is the application of basic science to practical problems. How do you say ‘Thank you!’ for a problem you didn’t get?”, Lindsey R. Baden, MD, And beyond health-related matters, psychology enjoys fantastic translation in areas such as human factors, education, organizational behavior, decision-making, environmental design, and social influence. Winter 2016/17: Transforming Medicine. This relates to targeted drug therapies, as well as targeted or molecular imaging, and interventional radiology. Help us improve your experience by providing feedback on this page. I would like to suggest that the discipline of psychology embrace translational research in a far more ambitious way. It is easy to find instances of basic research in psychology that has been translated into successful application and intervention. This is just one approach. It is not always obvious to the lay public, to federal funding agencies, to legislative leaders, or even to ourselves that psychology is translational science. For example, we have effective therapies for lupus and rheumatoid arthritis, but the question remains why some treatments work well for some patients and not others. Translational research is an emergent field with varying definitions depending on the source examined. John Eckenrode is a social psychologist and professor of human development and associate director of the Bronfenbrenner Center for Translational Research. I’m sure others can be developed. COVID-19 resources for psychologists, health-care workers and the public. Translational research was designed for the medical world. Translational research is elevated from a side-benefit of an individual study to an organized and coherent effort in its own right. Preliminary clinical report on safety and efficacy of photodynamic therapy using talaporfin sodium for malignant gliomas. Henderson’s vaccine research eradicated smallpox in a little over a decade, and made it so polio and measles outbreaks are now headline events. Every journal of psychology featuring at least one article, perhaps a regular section, on translational research. For example, molecular imaging in the interventional PET/CT suite may allow us to cryoablate or microwave ablate a tumor that is only visible based on this type of imaging.”, Paul B. Shyn, MD, PhD, We can address this by recognizing translational psychology in more formal ways. Every psychology journal can do it, because translation is everywhere in psychology. Akimoto, J., Haraoka, J., & Aizawa, K. (2012). These authors focused specifically on the conceptual and methodological challenges of translating social … Collections of such articles can be assembled into special volumes, to further promote the translational science of psychology. A popular research methods textbook, for instance, states that “the major goal of basic research is to acquire general information about a phenomenon, with little emphasis placed on applications to real-world examples of the phenomenon” (Bordens & Abbott, 2002, p. 19). A great example is the December 2006 American Psychologist article by Tashiro and Mortensen. Translational research is broader than the traditional term “applied research.” Applied research is any research that may possibly be useful for enhancing health or well-being. The point is to achieve greater visibility and coherence for translational psychology. To start off, what exactly is translational research? Many definitions have been given for translational research, but the definition I like best is that it is a systematic effort to convert basic research knowledge into practical applications to enhance human health and well being. As such, lung functioning and nutrition are critical elements to the care of these patients. Tashiro and Mortensen’s article is an example of what I have in mind. Brigham Health is published by the Brigham and Women’s Hospital Development Office. The basic research of psychology has long played a central role in the diagnosis, treatment, and prevention of disease. The technology we have now allows us to see these changes in remarkable detail, so we are learning how to develop biomarkers to help pick the right treatment for each patient—and our patients actively participate in that process.”, Deepak Rao, MD, PhD, Whereas, translational research includes two areas of translation. Rather than seeing this new priority as somehow representing a threat to psychology, we need to recognize that psychology is the model of translation. For example, we have effective therapies for lupus and rheumatoid arthritis, but the question remains why some treatments work well for some patients and not others. Advancing psychology to benefit society and improve lives, Call for Papers/Proposals/Nominations (9), © 2020 American Psychological Association. It worked so well, someone thought, “Why can’t we use this in the musculoskeletal world?” Now, instead of inserting a needle in an already painful joint, we can use this imaging technique and tell patients whether they have gout—and if so, how much—with no chance of infection or pain from the invasive test. Translational research activities are intended to bring knowledge from the lab into practice, and ideally, allow practice to influence what occurs in the laboratory. It’s a huge relief to patients and clinicians.”, Stacy Smith, MD, Boston, MA 02116 CF is a life-threatening autosomal recessive disorder, which results in thick mucus in the respiratory and digestive tracks. Rather than being threatened by the new emphasis at NIH, psychology should be flattered. There’s the advent of antibiotics, the introduction of insulin, the implementation of anesthesia, all the efforts enabling surgeries such as cardiopulmonary bypass. The first example involves behavioral treatment for regimen adherence in cystic fibrosis (CF). Section Chief, Musculoskeletal Imaging and Intervention, “Most relevant to my work is basic science research exploring ways to selectively target cancer cells based on molecular signatures. A great example is the December 2006 American Psychologist article by Tashiro and Mortensen. Senior Physician at Brigham and Women’s Hospital and Thomas D. and Virginia W. Cabot Professor of Health Sciences and Technology at Massachusetts Institute of Technology, “One of the powers of translational research is the inspiration we draw from patients. These authors focused specifically on the conceptual and methodological challenges of translating social psychology to improve psychotherapy. Writing in the June, 2006 issue of the Monitor on Psychology, I suggested that psychology is translational science. In an effort to address the issue of adopting research findings into practice, our team has successfully navigated the translational research spectrum in targeted conditions to improve care delivery.
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