Copyright © 2020 Elsevier B.V. or its licensors or contributors. We explain the rules for ambulance service and Medicare. All possible dosages and forms may not be included here. Your doctor should occasionally check your blood sugar levels while you take simvastatin. High doses -- also called high-intensity statin therapy -- included 40 to 80 milligrams (mg) of atorvastatin (Lipitor) or 20 to 40 mg of rosuvastatin (Crestor) daily. Your doctor will write the number of refills authorized on your prescription. What is Caprylic/Capric Triglyceride and Is It Safe? Don’t worry about airport x-ray machines. unexplained muscle weakness or tenderness, severe allergic reaction, with symptoms such as fever and trouble breathing, severe swelling of the hands, feet, and ankles, use of drugs that interact with simvastatin. See statins in Asian patients for more. It comes in two forms: a tablet and a suspension. Always discuss possible side effects with a healthcare provider who knows your medical history. Simvastatin belongs to the drug class known as HMG-CoA reductase inhibitors, also called statins. Although none of our patient had significant elevation of CPK. While you take simvastatin, your doctor will want to make sure that it isn’t affecting your liver and kidneys. These drugs should not be used with simvastatin. These plans provide the same coverage as…. Talk to your doctor about other cholesterol treatment options while breastfeeding. If you already have diabetes, your doctor should regularly check your blood sugar level. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. If you become pregnant while taking this drug, call your doctor right away. The difference between groups was significant (p = .045). ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. To study the effect of high dose Atorvastatin 40 mg versus 80 mg in patients with dyslipidemia. If you use these drugs with simvastatin, your doctor may lower your dosage of simvastatin. The more common side effects that can occur with simvastatin include: Call your doctor right away if you have serious side effects. They can discuss other treatment options during pregnancy. Store the tablets between 41°F and 86°F (5°C to 30°C). Studies Find New Drug May Help Lower Cholesterol. This can lead to very high levels of the drug in your body. Group A consisted patients who received Atorvastatin 40 mg daily and Group B Atorvastatin 80 mg daily. © 2005-2020 Healthline Media a Red Ventures Company. Tell your doctor right away if you experience: Simvastatin is a prescription drug. Simvastatin oral tablet is available as the brand-name drug Zocor. Statin Dose Intensity and Equivalency Chart*. Statins Can Reduce Risk of a Heart Attack for Adults of All Ages, Providence Medicare Advantage: A Guide to Your 2021 Plan Options, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, What to Do If Your Baby Shows Signs of Pink Eye. Avoid grapefruit juice while taking simvastatin. Both forms are taken by mouth. Talk to your doctor about other drug options that may work for you. Cardiovascular health among youths still has…, In a pair of articles published today in the New England Journal of Medicine, researchers tout the potential of bempedoic acid as a powerful new tool…, As far as natural alternatives to chemical ingredients go, capric acid and caprylic triglyceride is one of the cleanest ingredients that you can find…. Your doctor may discuss other medication options or lower your dosage of simvastatin. The good news is that you can reduce this with diet and exercise..it does work, been there, done it, wearing the T-shirt. Always carry the original prescription-labeled container with you. Using simvastatin with colchicine can increase the risk of both myopathy and rhabdomyolysis. However, because drugs affect each person differently, we can not guarantee that this information includes all possible side effects. Statins are a class of drugs that lower LDL, or “bad,” cholesterol levels in the body by preventing production in the liver, where the majority of the…. Since i had this event, and after speaking to DR at the hospital i have stopped smoking and changed my diet strictly to Boiled Veg, grilled chicken breast and Fish which are high in omega3. However, the dosage may range from 5 mg to 40 mg per day. Pravastatin sodium (Pravachol), commonly called pravastatin, is a member of the statin family of drugs 1 7.It is commonly prescribed to treat high cholesterol levels. Strengths: 10 mg, 20 mg, 40 mg, and 80 mg; Dosage for prevention of heart disease. Simvastatin may interact with other medications, Important considerations for taking simvastatin, What Is Vitamin F? If you don’t take it on schedule: Not taking simvastatin every day, skipping days, or taking doses at different times of the day may also increase your risk for high cholesterol levels, heart attack, or stroke. Pink eye in babies is common but can sometimes be more serious. https://doi.org/10.1016/j.ihj.2018.01.034. Your doctor may perform a baseline liver function test (an initial liver function test that is repeated in a few months). This can lead to an increased risk of bleeding. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. These drugs block your body from breaking down simvastatin. Adult dosage (ages 18–64 years) Typical starting dosage: 10–20 mg taken once per day. They also reduce the amount of cholesterol and triglycerides moving through the body. Monitoring and managing cholesterol levels is a primary focus in preventing heart attacks and strokes. After five years of high-dose Lipitor, the average LDL had fallen to 77 mg/dL compared with 101 mg/dl in the low-dose Lipitor group. Be sure to avoid doing this when the weather is very hot or very cold. Always speak with your doctor or pharmacist about dosages that are right for you. Use the pictures above to identify your dose. Taking it with food may reduce nausea. This Study is A Prospective, randomized, open-label, comparative study. Keep these considerations in mind if your doctor prescribes simvastatin for you. Always carry your medication with you. Disclaimer: Our goal is to provide you with the most relevant and current information. Simvastatin oral tablet can interact with other medications, vitamins, or herbs you may be taking. Simvastatin blocks the production of cholesterol, which is important for the developing baby. In some cases, they may not be available in every strength or form as the brand-name drug. To help avoid interactions, your doctor should manage all of your medications carefully. High cholesterol builds up in arteries causing plaques that narrow the passageways available for blood to flow freely to muscles and organs throughout the body. For people with low thyroid function (hypothyroidism) or diabetes: Simvastatin and other statin drugs can sometimes cause rhabdomyolysis. Can taking simvastatin increase my risk of diabetes? Generic drugs usually cost less than the brand-name version. At 3 and 6 month follow up, Atorvastatin 40 mg leads to mean LDL cholesterol reduction of 47.18 ± 20.81 & 50.03 ± 18.06 respectively. 80 mg dose should be limited to patients who have been taking it for ≥ 12 months without muscle toxicity Statins work to reduce the body’s cholesterol production. You can take simvastatin with or without food. Usual Adult Dose for Prevention of Cardiovascular Disease Initial dose: 10 mg or 20 mg orally once a day -An initial dose of 40 mg may be used in patients who require a larger reduction in low density lipoprotein (e.g.